Platform

Mini-Nucleosome Platform

At AAVINUE, we are pioneering a non-viral gene delivery platform designed to overcome the limitations of traditional delivery methods like AAV and lipid nanoparticles (LNPs). Our Mini-Nucleosome technology represents a breakthrough approach for the treatment of several neurodegenerative, ophthalmic and systemic diseases.

What Are Mini-Nucleosomes

Mini-Nucleosomes are engineered, nanosized particles created by chromatinizing DNA or RNA with core peptides through a unique condensation reaction. This process mimics the natural packaging of nucleic acids in cells, forming stable, highly compact structures.

Mini-Nucleosomes Are DNA or RNA Chromatinized Into Nanosized Particles via a Condensation Reaction

Mini-Nucleosomes Are DNA or RNA Chromatinized Into Nanosized Particles via a Condensation Reaction

Mini-Nucleosomes are engineered, nanosized particles created by chromatinizing DNA or RNA with core peptides through a unique condensation reaction. This process mimics the natural packaging of nucleic acids in cells, forming stable, highly compact structures.

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Scientist conducting experiment with pipette and petri dish.